Last update
5/25/2025
Research Authors

Overview

SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.6
USERS' SCORE
Good
Based on 92 Reviews
8
Supplement Facts
Serving Size:  2 Tablets
Amount Per Serving
%DV
Magnesium (from 2,000 mg magnesiumlysinate glycinate chelate) (Albion®)
200 mg
48%

Top Medical Research Studies

8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.

In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.

In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium sulfate shows potential benefits
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.

After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
Read More
7
Magnesium shows limited benefit for fatigue
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.

Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.

Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.

However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More

Most Useful Reviews

9
Irritability reduced
189 people found this helpful
This magnesium has been incredibly effective for me. It alleviated my irritability and fatigue, allowing me to fall asleep much more easily. It appears to have a cumulative effect, so consistency in taking it is key.
Read More
9
Stress relief
95 people found this helpful
After struggling with anxiety and chronic fatigue following a demanding work period, I tried Vitamin Fusion. Within four weeks, I experienced immense relief from both mental and physical stress, starting my days feeling stronger.
Read More
7.5
Decreased fatigue
92 people found this helpful
After one course of magnesium, my condition has improved somewhat. I fall asleep faster, and while there are occasional difficulties, they are less frequent. My overall fatigue has noticeably decreased, and I no longer wake up feeling exhausted.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 5 Researches
6.6
  • All Researches
8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.

In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.

In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium shows limited benefit for fatigue
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.

Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.

Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.

However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
7
Magnesium sulfate shows potential benefits
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.

After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
Read More
7
Magnesium shows promise for CFS
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.

Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.
Read More
4
Limited magnesium effectiveness in CFS
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).

Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.

While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.

Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
Read More

User Reviews

USERS' SCORE
Good
Based on 92 Reviews
8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Irritability reduced
189 people found this helpful
This magnesium has been incredibly effective for me. It alleviated my irritability and fatigue, allowing me to fall asleep much more easily. It appears to have a cumulative effect, so consistency in taking it is key.
Read More
9
Stress relief
95 people found this helpful
After struggling with anxiety and chronic fatigue following a demanding work period, I tried Vitamin Fusion. Within four weeks, I experienced immense relief from both mental and physical stress, starting my days feeling stronger.
Read More
7.5
Decreased fatigue
92 people found this helpful
After one course of magnesium, my condition has improved somewhat. I fall asleep faster, and while there are occasional difficulties, they are less frequent. My overall fatigue has noticeably decreased, and I no longer wake up feeling exhausted.
Read More
9
Life-changing relief
90 people found this helpful
After years of suffering with fatigue, this vitamin has finally given me relief. I'm regaining my life, feeling a significant boost in my mood and energy levels. I cannot recommend it enough!
Read More
9
Effective sleep aid
67 people found this helpful
Great sleep aid! This product has been the most effective sleep aid I have ever used for my chronic insomnia.
Read More

Frequently Asked Questions

9
Effective against fatigue
7 people found this helpful
After stopping eating, I had to adjust my body during the suspension period. I suffered from chronic fatigue, but this is beneficial for it. Multi vitamins, vitamin C powder, and magnesium work well; I've felt a difference in three weeks. I now wake up easier in the morning, feeling like I’ve slept deeply. However, I paused due to too many pills, but I plan to repurchase as magnesium and vitamin C seem crucial when one is tired.
9
Stress relief
95 people found this helpful
After struggling with anxiety and chronic fatigue following a demanding work period, I tried Vitamin Fusion. Within four weeks, I experienced immense relief from both mental and physical stress, starting my days feeling stronger.
9
Irritability reduced
189 people found this helpful
This magnesium has been incredibly effective for me. It alleviated my irritability and fatigue, allowing me to fall asleep much more easily. It appears to have a cumulative effect, so consistency in taking it is key.
9
Life-changing relief
90 people found this helpful
After years of suffering with fatigue, this vitamin has finally given me relief. I'm regaining my life, feeling a significant boost in my mood and energy levels. I cannot recommend it enough!
9
Sleep quality improved
12 people found this helpful
This magnesium has significantly alleviated my anxiety and chronic fatigue. Since I began taking it before bed, I can now enjoy deeper sleep without waking frequently. I awaken feeling refreshed, making this supplement an indispensable part of my life.
9
Effective for sleep
2 people found this helpful
This magnesium supplement is excellent! It effectively relieves my Restless Leg Syndrome, allowing me to fall asleep faster and enjoy a more restful night. Simply chewing a small piece before bed has been a game changer.
9
Symptoms disappeared
2 people found this helpful
This is the best magnesium I’ve used. My symptoms of magnesium deficiency included anxiety, seizures, and chronic fatigue syndrome, which were exacerbated by headaches and insomnia. After just a few days of taking this magnesium, my convulsions ceased, and soon, all my other symptoms disappeared. Magnesium is essential for everyone, both for prevention and recovery.
0
Unpleasant reactions
6 people found this helpful
I anticipated positive results from this magnesium, taking 1-2 tablets daily. Initially, I felt drowsiness, fatigue, and headaches during the day, and couldn't sleep at night, experiencing panic attacks by the third day. The condition was uncomfortable; I discovered these pills were the culprit. They are difficult to swallow and scratched my throat. A bad purchase, unfortunately.
9
Best magnesium!
3 people found this helpful
This magnesium supplement has proven the best for me after years of using different varieties. It alleviates my fatigue and aids in regulating my body's functions, including migraines and headaches. I typically take 2-3 tablets daily, and my mother finds it effective in helping her relax and sleep better in the evenings.
8
Magnesium potentially benefits CFS patients
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.

In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.

In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
4
Limited magnesium effectiveness in CFS
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).

Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.

While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.

Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
7
Magnesium shows limited benefit for fatigue
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.

Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.

Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.

However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
7
Magnesium shows promise for CFS
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.

Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.

References

  1. Alraek T, Lee MS, Choi TY, Cao H, Liu J. Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review. BMC Complement Altern Med. 2011;11:87. 10.1186/1472-6882-11-87
  2. Manuel y Keenoy B, Moorkens G, Vertommen J, Noe M, Nève J, et al. Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium. J Am Coll Nutr. 2000;19:374.
  3. Takahashi H, Imai K, Katanuma A, Sugaya T, Hisano K, et al. [A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate]. Arerugi. 1992;41:1605.
  4. Uchida A. [Therapy of chronic fatigue syndrome]. Nihon Rinsho. 1992;50:2679.
  5. Cox IM, Campbell MJ, Dowson D. Red blood cell magnesium and chronic fatigue syndrome. Lancet. 1991;337:757.
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